Sr. Scientist SiRNA

  • Location: San Diego, California
  • Type: Direct Hire
  • Job #18333

Sr/Principal Scientist – PhD  
Location: San Diego
Industry: Biotech (SiRNA)

Our startup biotech client with incredible technology and deep pockets has tasked Scientific Search in finding them a Sr. Scientist – Principal Scientist in their Chemistry group.  In this role you will be a key contributor to a diverse team working on novel siRNA modalities as well as oligo synthesis and conjugation. The ideal candidate will have experience of experience of siRNA/Oligo therapeutics. in this role you will work closely with colleagues to develop new drugs designs as well as to synthesize compounds.

  • Responsible for the synthesis, purification and characterization of organic compounds/oligonucleotides
  • Support ordering and general upkeep of RNA synthesizers and other related equipment
  • Synthesis projects independently or as part of a team
  • Act to mentor junior staff
  • Confident in analytical methods and analytical instrumentation [HPLC LC-MS MS NMR etc.]
  • Proven expertise in RNAi space
  • Clearly document experimental workflows and results; Communicate findings to the team and management when required
  • In vivo experience
  • Hire, recruit, coach and train junior employees


  • PhD degree: relevant life sciences discipline
  • 3+ years of revelant experience
  • Familiarity with siRNA, ASOs and gene silencing
  • Biotech experience is preferred
  • Salary Range: $110-140k base plus bonus, equity, 401k, medical benefits, etc. 

For immediate consideration please email Parker Jensen at